Early Immune Infiltrate and Tumor-Specific Immune Response Resulting in Improved Survival with Combination of Local Chemotherapy and Immune Checkpoint Blockade
نویسندگان
چکیده
منابع مشابه
Corticosteroids and immune checkpoint blockade
checkpoint blockade to stimulate the immune response have demonstrated promising outcomes in advanced malignancies [1]. As a result, novel cancer immunotherapy was named a scientific breakthrough of the year in 2013 by Science. Consistent with its mechanism of action of de novo stimulation or enhancement of pre-existing T cell responses, a number of immune-related adverse events (irAEs) have be...
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ژورنال
عنوان ژورنال: Journal of the American College of Surgeons
سال: 2015
ISSN: 1072-7515
DOI: 10.1016/j.jamcollsurg.2015.07.332